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i2b2 - Onyx ontology v2

Suggested version 2 of the Onyx ontology in i2b2.

Notes:

1. DUMMY Start Dates: these are where a start date does not really apply to the value being recorded. For example, if no relevant date is recorded or a date is not meaningful - such as for gender.

Onyx - ONX-00001

• Participant - ONX-00001
  • Discharges From Hospital - ONX-00002 (Node for each method)
    • Home - ONX-00003
      • [ConclusionQuestionnaire : epi_dischmeth.Home]
        • Start Date DUMMY: [ConclusionQuestionnaire:QuestionnaireRun.timeStart]
        • Modifier: 'Recruiting period of care'
    • Other_hospital - ONX-00004
      • [ConclusionQuestionnaire : epi_dischmeth.Other_hospital]
        • Start Date DUMMY: [ConclusionQuestionnaire:QuestionnaireRun.timeStart]
        • Modifier: 'Recruiting period of care'
    • Convalescence - ONX-00005
      • [ConclusionQuestionnaire : epi_dischmeth.Convalescence]
        • Start Date DUMMY: [ConclusionQuestionnaire:QuestionnaireRun.timeStart]
        • Modifier: 'Recruiting period of care'
    • Death - ONX-00006
      • [ConclusionQuestionnaire : epi_dischmeth.Death]
        • Start Date DUMMY: [ConclusionQuestionnaire:QuestionnaireRun.timeStart]
        • Modifier: 'Recruiting period of care'
    • Other_specialty - ONX-00007
      • [ConclusionQuestionnaire : epi_dischmeth.Other_specialty]
        • Start Date DUMMY: [ConclusionQuestionnaire:QuestionnaireRun.timeStart]
        • Modifier: 'Recruiting period of care'
    • Unknown - ONX-00008
      • [ConclusionQuestionnaire : epi_dischmeth.Unknown]
        • Start Date DUMMY: [ConclusionQuestionnaire:QuestionnaireRun.timeStart]
        • Modifier: 'Recruiting period of care'
  • Consent for Further Contact - ONX-00001 (Enumerated Value)
    • [ManualConsentQuestionnaire : Does the participant consent to further contact from BRU?]
      • Start Date: ?
  • Age - ONX-00001
  • Gender - ONX-00001
  • Ethnicity - ONX-00001
  • Recruitment Type - ONX-00001
  • Vital Status - ONX-00001

• Symptoms - ONX-00001 (Leaf per symptom)
  • Shortness of Breath - ONX-00001
    • [DataSubmissionQuestionnaire : epi_symptoms.Shortness_of_Breath]
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset] > ?
      • Modifier: 'Recruiting period of care presenting symptoms'
  • Collapse - ONX-00001
    • [DataSubmissionQuestionnaire : epi_symptoms.Collapse ]
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset] > ?
      • Modifier: 'Recruiting period of care presenting symptoms'
  • Syncope - ONX-00001
    • [DataSubmissionQuestionnaire : epi_symptoms.Syncope ]
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset] > ?
      • Modifier: 'Recruiting period of care presenting symptoms'
  • Chest_Pain - ONX-00001
    • [DataSubmissionQuestionnaire : epi_symptoms.Chest_Pain ]
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset] > ?
      • Modifier: 'Recruiting period of care presenting symptoms'
  • Palpitations - ONX-00001
    • [DataSubmissionQuestionnaire : epi_symptoms.Palpitations ]
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset] > ?
      • Modifier: 'Recruiting period of care presenting symptoms'
  • Cardiac_Arrest - ONX-00001
    • [DataSubmissionQuestionnaire : epi_symptoms.Cardiac_Arrest ]
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset] > ?
      • Modifier: 'Recruiting period of care presenting symptoms'
  • Dizziness - ONX-00001
    • [DataSubmissionQuestionnaire : epi_symptoms.Dizziness ]
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset] > ?
      • Modifier: 'Recruiting period of care presenting symptoms'
  • Epigastric_symptoms - ONX-00001
    • [DataSubmissionQuestionnaire : epi_symptoms.Epigastric_symptoms ]
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset] > ?
      • Modifier: 'Recruiting period of care presenting symptoms'
  • Leg_Pain_on_Walking - ONX-00001
    • [DataSubmissionQuestionnaire : epi_symptoms.Leg_Pain_on_Walking ]
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset] > ?
      • Modifier: 'Recruiting period of care presenting symptoms'
  • Nausea_Vomiting - ONX-00001
    • [DataSubmissionQuestionnaire : epi_symptoms.Nausea_Vomiting ]
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset] > ?
      • Modifier: 'Recruiting period of care presenting symptoms'
  • Paresthesia - ONX-00001
    • [DataSubmissionQuestionnaire : epi_symptoms.Paresthesia ]
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset] > ?
      • Modifier: 'Recruiting period of care presenting symptoms'
  • Side_Weakness - ONX-00001
    • [DataSubmissionQuestionnaire : epi_symptoms.Side_Weakness ]
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset] > ?
      • Modifier: 'Recruiting period of care presenting symptoms'
  • Slurred_Speech - ONX-00001
    • [DataSubmissionQuestionnaire : epi_symptoms.Slurred_Speech ]
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset] > ?
      • Modifier: 'Recruiting period of care presenting symptoms'
  • Sweating_Clammy - ONX-00001
    • [DataSubmissionQuestionnaire : epi_symptoms.Sweating_Clammy ]
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset] > ?
      • Modifier: 'Recruiting period of care presenting symptoms'
  • Tiredness_Lethargy - ONX-00001
    • [DataSubmissionQuestionnaire : epi_symptoms.Tiredness_Lethargy ]
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset] > ?
      • Modifier: 'Recruiting period of care presenting symptoms'
  • Additional Symptoms - ONX-00001 (Potential future target for NLP)
    • [DataSubmissionQuestionnaire : epi_symptomother_cat.OPEN_TEXT.OPEN_TEXT_SECDIAGOTHER]
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset] > ?
      • Modifier: 'Recruiting period of care presenting symptoms'

• Diagnoses - ONX-00001 (Folder per diagnosis. Then each folder has a 'Y', 'N', 'Prefer not to answer' & 'Don't know')
  • Troponin_pos_ACS- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Troponin_pos_ACS]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Troponin_pos_ACS]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Troponin_neg_ACS- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Troponin_neg_ACS]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Troponin_neg_ACS]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Acute_Arterial_Occlusion- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Acute_Arterial_Occlusion]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Acute_Arterial_Occlusion]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Acute_Stent_Thrombosis- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Acute_Stent_Thrombosis]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Acute_Stent_Thrombosis]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Aortic_Aneurysm - ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Aortic_Aneurysm]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Aortic_Aneurysm]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Aortic_Dissection- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Aortic_Dissection]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Aortic_Dissection]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Aortic_Infective_Endocarditis- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Aortic_Infective_Endocarditis]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Aortic_Infective_Endocarditis]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Aortic_Regurgitation- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Aortic_Regurgitation]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Aortic_Regurgitation]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Aortic_Stenosis- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Aortic_Stenosis]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Aortic_Stenosis]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Arrythmogenic_Right_Ventricular_Cardiomyopathy- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Arrythmogenic_Right_Ventricular_Cardiomyopathy]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Arrythmogenic_Right_Ventricular_Cardiomyopathy]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Atrial_Ectopics- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Atrial_Ectopics]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Atrial_Ectopics]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • AF - ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.AF]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.AF]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Atrial_Flutter - ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Atrial_Flutter]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Atrial_Flutter]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Haemorrhagic_Stroke - ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Haemorrhagic_Stroke]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Haemorrhagic_Stroke]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Thrombotic_Stroke - ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Thrombotic_Stroke]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Thrombotic_Stroke]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Cardiac_Arrest - ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Cardiac_Arrest]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Cardiac_Arrest]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Cardiac_Tamponade - ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Cardiac_Tamponade]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Cardiac_Tamponade]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Cardiogenic_Shock - ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Cardiogenic_Shock]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Cardiogenic_Shock]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • DVT - ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.DVT]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.DVT]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Type_I_Diabetes - ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Type_I_Diabetes]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Type_I_Diabetes]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Type_II_Diabetes - ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Type_II_Diabetes]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Type_II_Diabetes]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Dilated_Cardiomyopathy- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Dilated_Cardiomyopathy]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Dilated_Cardiomyopathy]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • 1st_DHB- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.1st_DHB]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.1st_DHB]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • 2nd_DHB_MT1- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.2nd_DHB_MT1]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.2nd_DHB_MT1]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • 2nd_DHB_MT2- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.2nd_DHB_MT2]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.2nd_DHB_MT2]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • 3rd_DHB- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.3rd_DHB]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.3rd_DHB]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Acute_Heart_Failure- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Acute_Heart_Failure]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Acute_Heart_Failure]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Chronic_Heart_Failure- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Chronic_Heart_Failure]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Chronic_Heart_Failure]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Hyperlipidaemia- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Hyperlipidaemia]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Hyperlipidaemia]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Essential_Hypertension- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Essential_Hypertension]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Essential_Hypertension]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Secondary_Hypertension- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Secondary_Hypertension]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Secondary_Hypertension]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Hypertrophic_Cardiomyopathy- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Hypertrophic_Cardiomyopathy]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Hypertrophic_Cardiomyopathy]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Infective_Endocarditis- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Infective_Endocarditis]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Infective_Endocarditis]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Intermittent_Claudication- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Intermittent_Claudication]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Intermittent_Claudication]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Ischaemic_Cardiomyopathy- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Ischaemic_Cardiomyopathy]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Ischaemic_Cardiomyopathy]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Late_Stent_Thrombosis- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Late_Stent_Thrombosis]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Late_Stent_Thrombosis]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Mitral_Infective_Endocarditis- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Mitral_Infective_Endocarditis]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Mitral_Infective_Endocarditis]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Mitral_Regurgitation- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Mitral_Regurgitation]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Mitral_Regurgitation]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Mitral_Stenosis- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Mitral_Stenosis]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Mitral_Stenosis]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Bacterial_Myocarditis- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Bacterial_Myocarditis]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Bacterial_Myocarditis]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Viral_Myocarditis- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Viral_Myocarditis]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Viral_Myocarditis]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Non_cardiac_Chest_Pain- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Non_cardiac_Chest_Pain]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Non_cardiac_Chest_Pain]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Pericardial_Effusion- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Pericardial_Effusion]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Pericardial_Effusion]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Bacterial_Pericarditis- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Bacterial_Pericarditis]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Bacterial_Pericarditis]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Post_infarction_Pericarditis- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Post_infarction_Pericarditis]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Post_infarction_Pericarditis]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Viral_Pericarditis- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Viral_Pericarditis]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Viral_Pericarditis]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Other_Pericarditis- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Other_Pericarditis]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Other_Pericarditis]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • PE- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.PE]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.PE]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Pulmonary_Infective_Endocarditis- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Pulmonary_Infective_Endocarditis]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Pulmonary_Infective_Endocarditis]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Pulmonary_Regurgitation- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Pulmonary_Regurgitation]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Pulmonary_Regurgitation]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Pulmonary_Stenosis- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Pulmonary_Stenosis]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Pulmonary_Stenosis]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Restrictive_Cardiomyopathy- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Restrictive_Cardiomyopathy]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Restrictive_Cardiomyopathy]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Ruptured_Aortic_Aneurysm- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Ruptured_Aortic_Aneurysm]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Ruptured_Aortic_Aneurysm]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • STEMI- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.STEMI]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.STEMI]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Stable_Angina- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Stable_Angina]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Stable_Angina]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Stable_CAD- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Stable_CAD]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Stable_CAD]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • SVT- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.SVT]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.SVT]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Symptomatic_bradycardia- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Symptomatic_bradycardia]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Symptomatic_bradycardia]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • TIA- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.TIA]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.TIA]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Tricuspid_Regurgitation- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Tricuspid_Regurgitation]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Tricuspid_Regurgitation]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Tricuspid_Stenosis- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Tricuspid_Stenosis]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Tricuspid_Stenosis]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • Ventricular_Ectopics- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.Ventricular_Ectopics]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.Ventricular_Ectopics]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • VF- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.VF]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.VF]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • VT- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.VT]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.VT]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
  • WPW- ONX-00001
    • [DataSubmissionQuestionnaire : epi_pridiag.WPW]
      • Modifier: 'Recruiting period of care presenting primary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]
    • [DataSubmissionQuestionnaire : epi_secdiag.WPW]
      • Modifier: 'Recruiting period of care presenting secondary diagnosis'
      • Start Date: [DataSubmissionQuestionnaire : epi_symponset]

• Hypertension - ONX-00001
  • [MedicalHistoryInterviewQuestionnaire : Have you ever suffered from high blood pressure]
    • Modifier: 'Patient questionnaire'
    • Start Date for 'Y' : [MedicalHistoryInterviewQuestionnaire: When did you first suffer from high blood pressure] > ?
    • Start Date for for other answers : [MedicalHistoryInterviewQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Treated' - [MedicalHistoryInterviewQuestionnaire: Have you received treatment for your high blood pressure]
  • [MedicalHistoryQuestionnaire: Is hypertension documented in the notes]
    • Modifier: 'Historic Medical Notes'
    • Start Date for 'Y' : [MedicalHistoryQuestionnaire: Year of onset of high blood pressure] > ?
    • Start Date for for other answers : [MedicalHistoryQuestionnaire: QuestionnaireRun.timeStart] > ?
• Diabetes - ONX-00001
  • [MedicalHistoryInterviewQuestionnaire : Have you ever suffered from diabetes]
    • Modifier: 'Patient questionnaire'
    • Start Date for 'Y' : [MedicalHistoryInterviewQuestionnaire: When did you first suffer from diabetes] > ?
    • Start Date for for other answers : [MedicalHistoryInterviewQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Type' - [MedicalHistoryInterviewQuestionnaire: Which type of diabetes]
    • Modifier: 'Treated' - [MedicalHistoryInterviewQuestionnaire: Have you received treatment for your diabetes]
  • [MedicalHistoryQuestionnaire: Is diabetes documented in the notes]
    • Modifier: 'Historic Medical Notes'
    • Start Date for 'Y' : [MedicalHistoryQuestionnaire: Year of onset of diabetes] > ?
    • Start Date for for other answers : [MedicalHistoryQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Type' - [MedicalHistoryQuestionnaire: Which type of diabetes]
• High Cholesterol - ONX-00001
  • [MedicalHistoryInterviewQuestionnaire : Have you ever suffered from high cholesterol]
    • Modifier: 'Patient questionnaire'
    • Start Date for 'Y' : [MedicalHistoryInterviewQuestionnaire: When did you first suffer from high cholesterol] > ?
    • Start Date for for other answers : [MedicalHistoryInterviewQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Treated' - [MedicalHistoryInterviewQuestionnaire: Have you received treatment for your high cholesterol]
  • [MedicalHistoryQuestionnaire: Is high cholesterol documented in the notes]
    • Modifier: 'Historic Medical Notes'
    • Start Date for 'Y' : [MedicalHistoryQuestionnaire: Year of onset of high cholesterol] > ?
    • Start Date for for other answers : [MedicalHistoryQuestionnaire: QuestionnaireRun.timeStart] > ?
• Myocardial Infarction - ONX-00001
  • [MedicalHistoryInterviewQuestionnaire : Have you ever suffered a heart attack or myocardial infarction (M.I.)]
    • One record for each [MedicalHistoryInterviewQuestionnaire : How many heart attacks or MIs have you had]
    • Modifier: 'Patient questionnaire'
    • Start Date for 'Y' : [MedicalHistoryInterviewQuestionnaire: Year of occurrence of each MI] > ?
    • Start Date for for other answers : [MedicalHistoryInterviewQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Treated' - [MedicalHistoryInterviewQuestionnaire: Have you received treatment for your MI]
  • [MedicalHistoryQuestionnaire: Is heart attack or myocardial infarction (M.I.) documented in the notes]
    • Modifier: 'Historic Medical Notes'
    • Start Date for 'Y' : [MedicalHistoryQuestionnaire: Year of occurrence of each MI] > ?
    • Start Date for for other answers : [MedicalHistoryQuestionnaire: QuestionnaireRun.timeStart] > ?
• Cerebrovascular Accident (CVA) - ONX-00001
  • [MedicalHistoryInterviewQuestionnaire : Have you ever had a stroke or a cerebrovascular accident (CVA)]
    • One record for each [MedicalHistoryInterviewQuestionnaire : How many CVAs]
    • Modifier: 'Patient questionnaire'
    • Start Date for 'Y' : [MedicalHistoryInterviewQuestionnaire: Year of occurrence of each CVA] > ?
    • Start Date for for other answers : [MedicalHistoryInterviewQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Treated' - [MedicalHistoryInterviewQuestionnaire: Have you received treatment for your CVA]
  • [MedicalHistoryQuestionnaire: Is stroke or a cerebrovascular accident (CVA) documented in the notes]
    • Modifier: 'Historic Medical Notes'
    • Start Date for 'Y' : [MedicalHistoryQuestionnaire: Year of occurrence of each CVA: (one per occurrence)] > ?
    • Start Date for for other answers : [MedicalHistoryQuestionnaire: QuestionnaireRun.timeStart] > ?
• Transient Ischaemic Attack (TIA) - ONX-00001
  • [MedicalHistoryInterviewQuestionnaire : Have you ever suffered from transient ischaemic attack (TIA)]
    • One record for each [MedicalHistoryInterviewQuestionnaire : How many TIAs have you suffered]
    • Modifier: 'Patient questionnaire'
    • Start Date for 'Y' : [MedicalHistoryInterviewQuestionnaire: Year of occurrence of each TIA] > ?
    • Start Date for for other answers : [MedicalHistoryInterviewQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Treated' - [MedicalHistoryInterviewQuestionnaire: ave you received treatment for your TIA]
  • [MedicalHistoryQuestionnaire: Is transient ischaemic attack (TIA) documented in the notes]
    • Modifier: 'Historic Medical Notes'
    • Start Date for 'Y' : [MedicalHistoryQuestionnaire: Year of occurrence of each TIA: (one per occurrence)] > ?
    • Start Date for for other answers : [MedicalHistoryQuestionnaire: QuestionnaireRun.timeStart] > ?
• Angina - ONX-00001
  • [MedicalHistoryInterviewQuestionnaire : Have you ever suffered from angina]
    • Modifier: 'Patient questionnaire'
    • Start Date for 'Y' : [MedicalHistoryInterviewQuestionnaire: When did you first suffer from angina] > ?
    • Start Date for for other answers : [MedicalHistoryInterviewQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Treated' - [MedicalHistoryInterviewQuestionnaire: Have you received treatment for your angina]
  • [MedicalHistoryQuestionnaire: Is angina documented in the notes]
    • Modifier: 'Historic Medical Notes'
    • Start Date for 'Y' : [MedicalHistoryQuestionnaire: Year of onset of angina] > ?
    • Start Date for for other answers : [MedicalHistoryQuestionnaire: QuestionnaireRun.timeStart] > ?
• Peripheral Vascular Disease (PVD) - ONX-00001
  • [MedicalHistoryInterviewQuestionnaire : Have you ever suffered from peripheral vascular disease (PVD)]
    • Modifier: 'Patient questionnaire'
    • Start Date for 'Y' : [MedicalHistoryInterviewQuestionnaire: When did you first suffer from peripheral vascular disease (PVD)] > ?
    • Start Date for for other answers : [MedicalHistoryInterviewQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Treated' - [MedicalHistoryInterviewQuestionnaire: Have you received treatment for your PVD]
  • [MedicalHistoryQuestionnaire: Is peripheral vascular disease (PVD) documented in the notes]
    • Modifier: 'Historic Medical Notes'
    • Start Date for 'Y' : [MedicalHistoryQuestionnaire: Year of onset of peripheral vascular disease (PVD)] > ?
    • Start Date for for other answers : [MedicalHistoryQuestionnaire: QuestionnaireRun.timeStart] > ?
• Valvular Heart Disease - ONX-00001
  • [MedicalHistoryInterviewQuestionnaire : Have you ever suffered from valvular heart disease]
    • Modifier: 'Patient questionnaire'
    • Start Date for 'Y' : [MedicalHistoryInterviewQuestionnaire: When did you first suffer from valvular heart disease] > ?
    • Start Date for for other answers : [MedicalHistoryInterviewQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Type' - [MedicalHistoryInterviewQuestionnaire: Which type of Valvular Heart Disease have you had]
    • Modifier: 'Treated' - [MedicalHistoryInterviewQuestionnaire: Have you received treatment for your valvular heart disease]
  • [MedicalHistoryQuestionnaire: Is valvular heart disease documented in the notes]
    • Modifier: 'Historic Medical Notes'
    • Start Date for 'Y' : [MedicalHistoryQuestionnaire: Year of onset of valvular heart disease] > ?
    • Start Date for for other answers : [MedicalHistoryQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Type' - [MedicalHistoryQuestionnaire: Which type of Valvular Heart Disease]
• Aortic Aneurysm - ONX-00001
  • [MedicalHistoryInterviewQuestionnaire : Have you ever suffered from an aortic aneurysm]
    • Modifier: 'Patient questionnaire'
    • Start Date for 'Y' : [MedicalHistoryInterviewQuestionnaire: When did you first suffer from aortic aneurysm] > ?
    • Start Date for for other answers : [MedicalHistoryInterviewQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Treated' - [MedicalHistoryInterviewQuestionnaire: Have you received treatment for your aortic aneurysm]
  • [MedicalHistoryQuestionnaire: Is an aortic aneurysm documented in the notes]
    • Modifier: 'Historic Medical Notes'
    • Start Date for 'Y' : [MedicalHistoryQuestionnaire: Year of onset of aortic aneurysm] > ?
    • Start Date for for other answers : [MedicalHistoryQuestionnaire: QuestionnaireRun.timeStart] > ?
• Chronic Renal Failure - ONX-00001
  • [MedicalHistoryInterviewQuestionnaire : Have you ever suffered from chronic renal failure]
    • Modifier: 'Patient questionnaire'
    • Start Date for 'Y' : [MedicalHistoryInterviewQuestionnaire: When did you first suffer from chronic renal failure] > ?
    • Start Date for for other answers : [MedicalHistoryInterviewQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Treated' - [MedicalHistoryInterviewQuestionnaire: Have you received treatment for your chronic renal failure]
  • [MedicalHistoryQuestionnaire: Is chronic renal failure documented in the notes]
    • Modifier: 'Historic Medical Notes'
    • Start Date for 'Y' : [MedicalHistoryQuestionnaire: Year of onset of chronic renal failure] > ?
    • Start Date for for other answers : [MedicalHistoryQuestionnaire: QuestionnaireRun.timeStart] > ?
• Chronic Obstructive airway disease (COAD) or chronic obstructive pulmonary disease (COPD) - ONX-00001
  • [MedicalHistoryInterviewQuestionnaire : Have you ever suffered from chronic obstructive airway disease (COAD) or chronic obstructive pulmonary disease (COPD)]
    • Modifier: 'Patient questionnaire'
    • Start Date for 'Y' : [MedicalHistoryInterviewQuestionnaire: When did you first suffer from COAD or COPD] > ?
    • Start Date for for other answers : [MedicalHistoryInterviewQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Treated' - [MedicalHistoryInterviewQuestionnaire: Have you received treatment for your COAD or COPD]
  • [MedicalHistoryQuestionnaire: Is chronic obstructive airway disease (COAD) or chronic obstructive pulmonary disease (COPD) documented in the notes]
    • Modifier: 'Historic Medical Notes'
    • Start Date for 'Y' : [MedicalHistoryQuestionnaire: Year of onset of chronic obstructive airway disease (COAD) or chronic obstructive pulmonary disease (COPD)] > ?
    • Start Date for for other answers : [MedicalHistoryQuestionnaire: QuestionnaireRun.timeStart] > ?
• liver disease - ONX-00001
  • [MedicalHistoryInterviewQuestionnaire : Have you ever suffered from liver disease]
    • Modifier: 'Patient questionnaire'
    • Start Date for 'Y' : [MedicalHistoryInterviewQuestionnaire: When did you first suffer from liver disease] > ?
    • Start Date for for other answers : [MedicalHistoryInterviewQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Treated' - [MedicalHistoryInterviewQuestionnaire: Have you received treatment for your liver disease]
  • [MedicalHistoryQuestionnaire: Is liver disease documented in the notes]
    • Modifier: 'Historic Medical Notes'
    • Start Date for 'Y' : [MedicalHistoryQuestionnaire: Year of onset of liver disease] > ?
    • Start Date for for other answers : [MedicalHistoryQuestionnaire: QuestionnaireRun.timeStart] > ?
• asthma - ONX-00001
  • [MedicalHistoryInterviewQuestionnaire : Have you ever suffered from asthma]
    • Modifier: 'Patient questionnaire'
    • Start Date for 'Y' : [MedicalHistoryInterviewQuestionnaire: When did you first suffer from asthma] > ?
    • Start Date for for other answers : [MedicalHistoryInterviewQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Treated' - [MedicalHistoryInterviewQuestionnaire: Have you received treatment for your asthma]
  • [MedicalHistoryQuestionnaire: Is asthma documented in the notes]
    • Modifier: 'Historic Medical Notes'
    • Start Date for 'Y' : [MedicalHistoryQuestionnaire: Year of onset of asthma] > ?
    • Start Date for for other answers : [MedicalHistoryQuestionnaire: QuestionnaireRun.timeStart] > ?
• Atrial Fibrillation (AF) - ONX-00001
  • [MedicalHistoryInterviewQuestionnaire : Have you ever suffered from Atrial Fibrillation (AF)]
    • Modifier: 'Patient questionnaire'
    • Start Date for 'Y' : [MedicalHistoryInterviewQuestionnaire: When did you first suffer from AF] > ?
    • Start Date for for other answers : [MedicalHistoryInterviewQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Treated' - [MedicalHistoryInterviewQuestionnaire: Have you received treatment for your AF]
  • [MedicalHistoryQuestionnaire: Is Atrial Fibrillation (AF) documented in the notes]
    • Modifier: 'Historic Medical Notes'
    • Start Date for 'Y' : [MedicalHistoryQuestionnaire: Year of onset of AF] > ?
    • Start Date for for other answers : [MedicalHistoryQuestionnaire: QuestionnaireRun.timeStart] > ?
• heart rhythm disturbance - ONX-00001
  • [MedicalHistoryInterviewQuestionnaire : Have you ever suffered from any other heart rhythm disturbance]
    • Modifier: 'Patient questionnaire'
    • Start Date for 'Y' : [MedicalHistoryInterviewQuestionnaire: heart rhythm disturbance] > ?
    • Start Date for for other answers : [MedicalHistoryInterviewQuestionnaire: QuestionnaireRun.timeStart] > ?
    • Modifier: 'Treated' - [MedicalHistoryInterviewQuestionnaire: Have you received treatment for your other heart rhythm disturbance]
  • [MedicalHistoryQuestionnaire: Is there any other heart rhythm disturbance documented in the notes]
    • Modifier: 'Historic Medical Notes'
    • Start Date for 'Y' : [MedicalHistoryQuestionnaire: Year of onset of heart rhythm disturbance] > ?
    • Start Date for for other answers : [MedicalHistoryQuestionnaire: QuestionnaireRun.timeStart] > ?
• Details of other diagnoses - ONX-00001 (Potential future target for NLP)
  • [DataSubmissionQuestionnaire : Please supply details of the other secondary diagnosis]
    • Modifier: 'Recruiting period of care presenting other secondary diagnosis'
    • Start Date: [DataSubmissionQuestionnaire : When was the First Onset of Symptoms] > ?

• Prescribing - ONX-00001 (Leaf per drug)
  • [ConclusionQuestionnaire : Drugs on Discharge]
    • Start Date: [DataSubmissionQuestionnaire : When was the First Onset of Symptoms] > ?
    • Modifier: 'Recruiting period of care discharge'
• Procedures - ONX-00001
  • CABG Coronary Artery Bypass Graft - ONX-00001 (Start Date)
    • [DataSubmissionQuestionnaire : CABG Coronary Artery Bypass Graft]
      • Modifier: 'Notes from period of care'?
    • [MedicalHistoryInterviewQuestionnaire: Enter the year for each CABG] - one for each occurrence
      • Modifier: 'Patient questionnaire'
    • [MedicalHistoryQuestionnaire: Enter the year for each CABG] - one for each occurrence
      • Modifier: 'Historic Medical Notes'
  • Valve Surgery - ONX-00001 (Start Date)
    • [DataSubmissionQuestionnaire : Valve Surgery]
      • Modifier: 'Notes from period of care'?
    • [MedicalHistoryInterviewQuestionnaire: Enter the year for each Valve_Surgery] - one for each occurrence
      • Modifier: 'Patient questionnaire'
    • [MedicalHistoryQuestionnaire: Enter the year for each Valve_Surgery] - one for each occurrence
      • Modifier: 'Historic Medical Notes'
  • TAVI - Transcatheter Aortic Valve Implantation - ONX-00001 (Start Date)
    • [DataSubmissionQuestionnaire : TAVI - Transcatheter Aortic Valve Implantation]
      • Modifier: 'Notes from period of care'?
    • [MedicalHistoryInterviewQuestionnaire: In which year was your TAVI performed]
      • Modifier: 'Patient questionnaire'
    • [MedicalHistoryQuestionnaire: Enter the year TAVI was performed]
      • Modifier: 'Historic Medical Notes'
  • PPCI - Primary Percutaneous Coronary Intervention - ONX-00001 (Start Date)
    • [DataSubmissionQuestionnaire : PPCI - Primary Percutaneous Coronary Intervention]
      • Modifier: 'Notes from period of care'?
    • [MedicalHistoryInterviewQuestionnaire: Enter the year for each Primary PCI] - one for each occurrence
      • Modifier: 'Patient questionnaire'
    • [MedicalHistoryQuestionnaire: Enter the year for each Primary PCI] - one for each occurrence
      • Modifier: 'Historic Medical Notes'
  • Other PCI - ONX-00001 (Start Date)
    • [DataSubmissionQuestionnaire : Other PCI]
      • Modifier: 'Notes from period of care'?
    • [MedicalHistoryInterviewQuestionnaire: When did you have the other PCI procedures] - one for each occurrence
      • Modifier: 'Patient questionnaire'
    • [MedicalHistoryQuestionnaire: Enter the year of each other PCI] - one for each occurrence
      • Modifier: 'Historic Medical Notes'
  • Pacemaker insertion - ONX-00001 (Start Date)
    • [DataSubmissionQuestionnaire : Pacemaker insertion]
      • Modifier: 'Notes from period of care'?
    • [MedicalHistoryInterviewQuestionnaire: Enter the year for each pacemaker] - one for each occurrence
      • Modifier: 'Patient questionnaire'
    • [MedicalHistoryQuestionnaire: Enter the year for each pacemaker] - one for each occurrence
      • Modifier: 'Historic Medical Notes'
  • ICD - Implantable Cardioverter Defibrillator - ONX-00001 (Start Date)
    • [DataSubmissionQuestionnaire : ICD - Implantable Cardioverter Defibrillator]
      • Modifier: 'Notes from period of care'?
    • [MedicalHistoryInterviewQuestionnaire: Enter the year for each ICD] - one for each occurrence
      • Modifier: 'Patient questionnaire'
    • [MedicalHistoryQuestionnaire: Enter the year for each ICD] - one for each occurrence
      • Modifier: 'Historic Medical Notes'
  • DC Cardioversion - ONX-00001 (Start Date)
    • [DataSubmissionQuestionnaire : DC Cardioversion]
      • Modifier: 'Notes from period of care'?
    • [MedicalHistoryInterviewQuestionnaire: Enter the year for each DC cardioversion] - one for each occurrence
      • Modifier: 'Patient questionnaire'
    • [MedicalHistoryQuestionnaire: Enter the year for each DC cardioversion] - one for each occurrence
      • Modifier: 'Historic Medical Notes'
  • LVAD - Left Ventricular Assist Device - ONX-00001 (Start Date)
    • [DataSubmissionQuestionnaire : LVAD - Left Ventricular Assist Device]
      • Modifier: 'Notes from period of care'?
    • [MedicalHistoryInterviewQuestionnaire: Enter the year for each LVAD] - one for each occurrence
      • Modifier: 'Patient questionnaire'
    • [MedicalHistoryQuestionnaire: Enter the year for each LVAD] - one for each occurrence
      • Modifier: 'Historic Medical Notes'
  • Thrombolysis - ONX-00001 (Start Date)
    • [DataSubmissionQuestionnaire : Thrombolysis]
      • Modifier: 'Notes from period of care'?
    • [MedicalHistoryInterviewQuestionnaire: Enter the year for each thrombolysis treatment] - one for each occurrence
      • Modifier: 'Patient questionnaire'
    • [MedicalHistoryQuestionnaire: Enter the year for each thrombolysis treatment] - one for each occurrence
      • Modifier: 'Historic Medical Notes'
  • Electrophysiology (EP) / Radiofrequency (RF) Ablation - ONX-00001(Start Date)
    • [DataSubmissionQuestionnaire : Electrophysiology (EP) / Radiofrequency (RF) Ablation]
      • Modifier: 'Notes from period of care'?
  • Coronary Angiography - ONX-00001 (Start Date)
    • [DataSubmissionQuestionnaire : Coronary Angiography]
      • Modifier: 'Notes from period of care'?
  • ablation - ONX-00001 (Start Date)
    • [MedicalHistoryInterviewQuestionnaire: Enter the year for each ablation] - one for each occurrence
      • Modifier: 'Patient questionnaire'
    • [MedicalHistoryQuestionnaire: Enter the year for each ablation] - one for each occurrence
      • Modifier: 'Historic Medical Notes'
  • Aortic Balloon Pump - ONX-00001 (Start Date)
    • [MedicalHistoryInterviewQuestionnaire: Enter the year for each Aortic Balloon Pump] - one for each occurrence
      • Modifier: 'Patient questionnaire'
    • [MedicalHistoryQuestionnaire: Enter the year for each Aortic Balloon Pump] - one for each occurrence
      • Modifier: 'Historic Medical Notes'
  • bare metal stent - ONX-00001 (Start Date)
    • [MedicalHistoryInterviewQuestionnaire: Enter the year for each bare metal stent] - one for each occurrence
      • Modifier: 'Patient questionnaire'
    • [MedicalHistoryQuestionnaire: Enter the year for each bare metal stent] - one for each occurrence
      • Modifier: 'Historic Medical Notes'
  • drug-eluting stent - ONX-00001 (Start Date)
    • [MedicalHistoryInterviewQuestionnaire: Enter the year for each drug-eluting stent fitted] - one for each occurrence
      • Modifier: 'Patient questionnaire'
    • [MedicalHistoryQuestionnaire: Enter the year for each drug-eluting stent] - one for each occurrence
      • Modifier: 'Historic Medical Notes'
  • CPAP - ONX-00001 (Start Date)
    • [MedicalHistoryInterviewQuestionnaire: Enter the year for each CPAP] - one for each occurrence
      • Modifier: 'Patient questionnaire'
    • [MedicalHistoryQuestionnaire: Enter the year for each CPAP] - one for each occurrence
      • Modifier: 'Historic Medical Notes'
  • heart transplant - ONX-00001 (Start Date)
    • [MedicalHistoryInterviewQuestionnaire: Enter the year for each heart transplant] - one for each occurrence
      • Modifier: 'Patient questionnaire'
    • [MedicalHistoryQuestionnaire: Enter the year for each heart transplant] - one for each occurrence
      • Modifier: 'Historic Medical Notes'
• Observations - ONX-00001
  • Heart Rate - ONX-00001 (Numeric)
    • [DataSubmissionQuestionnaire : First recorded Heart Rate during this episode of care]
      • Start Date: ?
      • Modifier: 'Notes from period of care'?
    • [DataSubmissionQuestionnaire : Latest recorded Heart Rate]
      • Start Date: ?
      • Modifier: 'Notes from period of care'?
  • Systolic Blood Pressure - ONX-00001 (Numeric)
    • [DataSubmissionQuestionnaire : First recorded Systolic Blood Pressure]
      • Start Date: ?
      • Modifier: 'Notes from period of care'?
    • [DataSubmissionQuestionnaire : Latest recorded Systolic Blood Pressure]
      • Start Date: ?
      • Modifier: 'Notes from period of care'?
  • Diastolic Blood Pressure - ONX-00001 (Numeric)
    • [DataSubmissionQuestionnaire : First recorded Diastolic Blood Pressure]
      • Start Date: ?
      • Modifier: 'Notes from period of care'?
    • [DataSubmissionQuestionnaire : Latest recorded Diastolic Blood Pressure]
      • Start Date: ?
      • Modifier: 'Notes from period of care'?
  • Height - ONX-00001 (Numeric)
    • [DataSubmissionQuestionnaire : Height]
      • Start Date: ?
      • Modifier: 'Notes from period of care'?
  • Weight - ONX-00001 (Numeric)
    • [DataSubmissionQuestionnaire : Weight]
      • Start Date: ?
      • Modifier: 'Notes from period of care'?
  • Measurement around the waist - ONX-00001 (Numeric)
    • [EndContactQuestionnaire: Measurement around the waist]
      • Start Date: [EndContactQuestionnaire: QuestionnaireRun.timeStart]
      • Modifier: 'Interview'?
  • Measurement around the hips - ONX-00001 (Numeric)
    • [EndContactQuestionnaire: Measurement around the hips]
      • Start Date: [EndContactQuestionnaire: QuestionnaireRun.timeStart]
      • Modifier: 'Interview'?
  • Skin-fold measurement - biceps - ONX-00001 (Numeric)
    • [EndContactQuestionnaire: Skin-fold measurement - biceps]
      • Start Date: [EndContactQuestionnaire: QuestionnaireRun.timeStart]
      • Modifier: 'Interview'?
  • Skin-fold measurement - triceps - ONX-00001 (Numeric)
    • [EndContactQuestionnaire: Skin-fold measurement - triceps]
      • Start Date: [EndContactQuestionnaire: QuestionnaireRun.timeStart]
      • Modifier: 'Interview'?
  • Skin-fold measurement - subscapular - ONX-00001 (Numeric)
    • [EndContactQuestionnaire: Skin-fold measurement - subscapular]
      • Start Date: [EndContactQuestionnaire: QuestionnaireRun.timeStart]
      • Modifier: 'Interview'?
  • Skin-fold measurement - supra-iliac - ONX-00001 (Numeric)
    • [EndContactQuestionnaire: Skin-fold measurement - supra-iliac]
      • Start Date: [EndContactQuestionnaire: QuestionnaireRun.timeStart]
      • Modifier: 'Interview'?
  • Skin-fold measurement - supra-iliac - ONX-00001 (Numeric)
    • [EndContactQuestionnaire: Skin-fold measurement - supra-iliac]
      • Start Date: [EndContactQuestionnaire: QuestionnaireRun.timeStart]
      • Modifier: 'Interview'?
• Risk Factors - ONX-00001
  • Tobacco - ONX-00001
    • Has smoked or used any tobacco or nicotine product - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
      • [RiskFactorQuestionnaire: Have you ever smoked or used any tobacco or nicotine product]
        • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
      • Cigarettes - ONX-00001
        • Has smoked at some time - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
          • [RiskFactorQuestionnaire: Which of the following have you ever smoked or used]
          • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
        • Has smoked cigarettes on most days - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
          • [RiskFactorQuestionnaire: Have you ever smoked cigarettes on most days]
          • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
        • Currently smoke cigarettes - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
          • [RiskFactorQuestionnaire: Do you currently smoke cigarettes]
          • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
        • Maximum cigarettes per day - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
          • [RiskFactorQuestionnaire: On average, how many cigarettes did you smoke per day when you were smoking the most]
          • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
        • Age of regular smoking onset - ONX-00001 (Numeric)
          • [RiskFactorQuestionnaire: How old were you when you began smoking cigarettes on most days]
          • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
        • Age of smoking cessation - ONX-00001 (Numeric)
          • [RiskFactorQuestionnaire: How old were you when you stopped smoking cigarettes]
          • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
        • cigarettes currently smoked per day - ONX-00001 (Numeric)
          • [RiskFactorQuestionnaire: On average, how many cigarettes do you currently smoke per day]
          • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
        • Time since last cigarette - ONX-00001 (Recent time)
          • [RiskFactorQuestionnaire: When was the last time you had a cigarette]
          • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
      • Cigars - ONX-00001
        • Has smoked at some time - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
          • [RiskFactorQuestionnaire: Which of the following have you ever smoked or used]
          • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
        • Has smoked cigars on most days - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
          • [RiskFactorQuestionnaire: Have you ever smoked cigars regularly]
          • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
        • Currently smokes cigars - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
          • [RiskFactorQuestionnaire: Do you currently smoke cigars]
          • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
        • Maximum cigars per day - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
          • [RiskFactorQuestionnaire: On average, how many cigars did you smoke per day when you were smoking the most]
          • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
        • Age of regular smoking of cigars onset - ONX-00001 (Numeric)
          • [RiskFactorQuestionnaire: How old were you when you began smoking cigars on most days]
          • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
        • Age of smoking cigars cessation - ONX-00001 (Numeric)
          • [RiskFactorQuestionnaire: How old were you when you stopped smoking cigars]
          • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
        • cigars currently smoked per day - ONX-00001 (Numeric)
          • [RiskFactorQuestionnaire: On average, how many cigars do you currently smoke per day]
          • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
        • Time since last cigar - ONX-00001 (Recent time)
          • [RiskFactorQuestionnaire: When was the last time you had a cigar]
          • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

• Pipe - ONX-00001
  • Has smoked at some time - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
    • [RiskFactorQuestionnaire: Which of the following have you ever smoked or used]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Has smoked a pipe on most days - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
    • [RiskFactorQuestionnaire: Have you ever smoked a pipe regularly]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Currently smokes a pipe - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
    • [RiskFactorQuestionnaire: Do you currently smoke a pipe]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Maximum pipe tobacco per day - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
    • [RiskFactorQuestionnaire: How much tobacco did you smoke per day when you were smoking the most]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Age of regular pipe smoking onset - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How old were you when you began smoking a pipe on most days]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Age of smoking a pipe cessation - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How old were you when you stopped smoking a pipe]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Pipe tobacco currently smoked per day - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How much tobacco do you currently smoke per day]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Time since last pipe - ONX-00001(Recent time)
    • [RiskFactorQuestionnaire: When was the last time you smoked a pipe]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

• Snuff or Chewing Tobabcco - ONX-00001
  • Has used at some time - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
    • [RiskFactorQuestionnaire: Which of the following have you ever smoked or used]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Has used snuff or chewing tobacco on most days - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
    • [RiskFactorQuestionnaire: Have you ever used snuff or chewing tobacco regularly]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Currently uses snuff or chewing tobacco - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
    • [RiskFactorQuestionnaire: Do you currently use snuff or chewing tobacco]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Maximum snuff or chewing tobacco usage - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
    • [RiskFactorQuestionnaire: How much snuff or chewing tobacco did you smoke per day when you were using the most]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Age of snuff or chewing tobacco usage onset - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How old were you when you began using snuff or chewing tobacco]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Age of snuff or chewing tobacco usage cessation - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How old were you when you stopped using snuff or chewing tobacco]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • snuff or chewing tobacco currently used per day - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How much snuff or chewing tobacco do you use per week]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Time since last pipe - ONX-00001 (Recent time)
    • [RiskFactorQuestionnaire: When was the last time you has snuff or chewing tobacco]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

• Other tobacco or Nicotine Product - ONX-00001
  • Has used at some time - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
    • [RiskFactorQuestionnaire: Which of the following have you ever smoked or used]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Has used other tobacco or nicotine product for at least 6 months - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
    • [RiskFactorQuestionnaire: Have you ever used any other tobacco or nicotine product for at least 6 months]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Currently uses other tobacco or nicotine product - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
    • [RiskFactorQuestionnaire: Do you currently use any other tobacco or nicotine product]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Maximum tobacco or nicotine product usage per week - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
    • [RiskFactorQuestionnaire: How much of the tobacco or nicotine product per week did you use when you were using the most]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Age of tobacco or nicotine product usage onset - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How old were you when you began using the tobacco or nicotine product]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Age of tobacco or nicotine product usage cessation - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How old were you when you stopped using the tobacco or nicotine product]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Current tobacco or nicotine product usage per week - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How much of the tobacco or nicotine product do you use per week]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Time since last tobacco or nicotine usage - ONX-00001 (Recent time)
    • [RiskFactorQuestionnaire: When was the last time you had any tobacco or nicotine]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

• Alcohol - ONX-00001
  • Has drunk alcohol - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
    • [RiskFactorQuestionnaire: Have you ever drunk alcohol]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Has drunk alcohol at least once per week - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
    • [RiskFactorQuestionnaire: Have you ever drunk alcohol at least once per week]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Currently drinks alcohol at least once per week - ONX-00001 ('Y', 'N', 'Prefer not to answer' & 'Don't know')
    • [RiskFactorQuestionnaire: Do you currently drink alcohol at least once per week]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Current pints of beer drunk in a typical week - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How many pints of beer do you drink in a typical week]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Current glasses of white wine drunk in a typical week - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How many glasses of white wine do you drink in a typical week]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Current glasses of red wine in a typical week - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How many glasses of red wine do you drink in a typical week]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Current glasses of rose wine in a typical week - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How many glasses of rose wine do you drink in a typical week]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Current measures of spirits in a typical week - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How many measures of spirits do you drink in a typical week]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Age of Alcohol usage onset - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How old were you when you began drinking alcohol]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Time since last alcohol usage - ONX-00001 (Recent time)
    • [RiskFactorQuestionnaire: When was the last time you had a drink containing alcohol]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

• Diet - ONX-00001
  • Type of diet - ONX-00001 (Enumerated list)
    • [RiskFactorQuestionnaire: How would you describe your diet]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

• Activity - ONX-00001
  • Work involves physical activity - ONX-00001 (yes/no)
    • [RiskFactorQuestionnaire: If you work, does your work involve any physical activity]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Undertakes regular exercise - ONX-00001 (yes/no)
    • [RiskFactorQuestionnaire: Apart from work, do you undertake any regular physical exercise over and above that of daily living]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

• Familiy History - ONX-00001
  • Number of brothers - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How many brothers do you have]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Number of sisters - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How many sisters do you have]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Number of children - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How many children do you have]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Relatives suffered angina or other Coronary Artery Disease - ONX-00001 (y, n, pnta, dk)
    • [RiskFactorQuestionnaire: Have any of your relatives suffered angina or other Coronary Artery Disease]
      • Modifier: Father, Mother, Brother, Sister, Child
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Relatives suffered a heart attack or Myocardial Infarction - ONX-00001 (y, n, pnta, dk)
    • [RiskFactorQuestionnaire: Have any of your relatives suffered a heart attack or Myocardial Infarction]
      • Modifier: Father, Mother, Brother, Sister, Child
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Relatives been diagnosed with heart failure - ONX-00001 (y, n, pnta, dk)
    • [RiskFactorQuestionnaire: Have any of your relatives ever been diagnosed with heart failure]
      • Modifier: Father, Mother, Brother, Sister, Child
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Relatives suffered Atrial Fibrillation (AF) - ONX-00001 (y, n, pnta, dk)
    • [RiskFactorQuestionnaire: Have any of your relatives ever suffered Atrial Fibrillation (AF)]
      • Modifier: Father, Mother, Brother, Sister, Child
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Relatives suffered a stroke or CVA - ONX-00001 (y, n, pnta, dk)
    • [RiskFactorQuestionnaire: Have any of your relatives ever suffered a stroke or CVA]
      • Modifier: Father, Mother, Brother, Sister, Child
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Relatives diagnosed with high blood pressure - ONX-00001 (y, n, pnta, dk)
    • [RiskFactorQuestionnaire: Have any of your relatives been diagnosed with high blood pressure]
      • Modifier: Father, Mother, Brother, Sister, Child
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Relatives diagnosed with valvular heart disease - ONX-00001 (y, n, pnta, dk)
    • [RiskFactorQuestionnaire: Have any of your relatives been diagnosed with valvular heart disease]
      • Modifier: Father, Mother, Brother, Sister, Child
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

• Relatives age of onset of angina or Coronary Artery Disease - ONX-00001 (numeric)
  • [RiskFactorQuestionnaire: At what age did they first suffer from angina or Coronary Artery Disease]
    • Modifier: Father, Mother, Brother, Sister, Child
  • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
• Relatives received treatment for angina or Coronary Artery Disease - ONX-00001 (y, n, pnta, dk)
  • [RiskFactorQuestionnaire: Have they received treatment for their angina or Coronary Artery Disease]
    • Modifier: Father, Mother, Brother, Sister, Child
  • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

• Relatives age of first heart attack or Myocardial Infarction - ONX-00001 (numeric)
  • [RiskFactorQuestionnaire: At what age did they suffer their first heart attack or Myocardial Infarction]
    • Modifier: Father, Mother, Brother, Sister, Child
  • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
• Relatives received treatment for heart attack or Myocardial Infarction - ONX-00001 (y, n, pnta, dk)
  • [RiskFactorQuestionnaire: Have they received treatment for their heart attack or Myocardial Infarction]
    • Modifier: Father, Mother, Brother, Sister, Child
  • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

• Relatives age of first suffer from heart failure - ONX-00001 (numeric)
  • [RiskFactorQuestionnaire: At what age did they first suffer from heart failure]
    • Modifier: Father, Mother, Brother, Sister, Child
  • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
• Relatives received treatment for their heart failure - ONX-00001 (y, n, pnta, dk)
  • [RiskFactorQuestionnaire: Have they received treatment for their heart failure]
    • Modifier: Father, Mother, Brother, Sister, Child
  • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

• Relatives age of first suffer from Atrial Fibrillation - ONX-00001 (numeric)
  • [RiskFactorQuestionnaire: At what age did they first suffer from Atrial Fibrillation]
    • Modifier: Father, Mother, Brother, Sister, Child
  • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
• Relatives received treatment for their Atrial Fibrillation - ONX-00001 (y, n, pnta, dk)
  • [RiskFactorQuestionnaire: Have they received treatment for their Atrial Fibrillation]
    • Modifier: Father, Mother, Brother, Sister, Child
  • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

• Relatives age suffer their first stroke or CVA - ONX-00001 (numeric)
  • [RiskFactorQuestionnaire: At what age did they suffer their first stroke or CVA]
    • Modifier: Father, Mother, Brother, Sister, Child
  • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
• Relatives received treatment for the stroke or CVA - ONX-00001 (y, n, pnta, dk)
  • [RiskFactorQuestionnaire: Were they treated for the stroke or CVA]
    • Modifier: Father, Mother, Brother, Sister, Child
  • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

• Relatives age first suffer from high blood pressure - ONX-00001 (numeric)
  • [RiskFactorQuestionnaire: At what age did they first suffer from high blood pressure]
    • Modifier: Father, Mother, Brother, Sister, Child
  • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
• Relatives received treatment for high blood pressure - ONX-00001 (y, n, pnta, dk)
  • [RiskFactorQuestionnaire: Have they received treatment for their high blood pressure]
    • Modifier: Father, Mother, Brother, Sister, Child
  • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

• Relatives age first suffer from valvular heart disease - ONX-00001 (numeric)
  • [RiskFactorQuestionnaire: At what age did they first suffer from valvular heart disease]
    • Modifier: Father, Mother, Brother, Sister, Child
  • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
• Relatives received treatment for valvular heart disease - ONX-00001 (y, n, pnta, dk)
  • [RiskFactorQuestionnaire: Have they received treatment for their valvular heart disease]
    • Modifier: Father, Mother, Brother, Sister, Child
  • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

The cause of relative's death is a tricky one. Here are some options:

• Cause of close relative's death - ONX-00001 (Leaf for each type)
  • [RiskFactorQuestionnaire: Do you know the cause of your xxxx's death]
    • Modifier: Father, Mother, Brother, Sister, Child
    • Modifier 'Sudden': [RiskFactorQuestionnaire: Was their death sudden and unexpected]
    • Modifier 'Age': [RiskFactorQuestionnaire: At what age did they die]
  • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

Depending on how modifiers work, the filtering on age might not be adequate. Another option:

• Age of close relative's death - ONX-00001 (Numeric)
  • [RiskFactorQuestionnaire: At what age did they die]
    • Modifier: Father, Mother, Brother, Sister, Child
    • Modifier 'Sudden': [RiskFactorQuestionnaire: Was their death sudden and unexpected]
    • Modifier 'Cause': [RiskFactorQuestionnaire: Do you know the cause of your xxxx's death]
  • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

This allows us to filter on age better, but the cause is more hidden. Also, how do we record a death where the cause is known, but not the age? Could have a record of age > 0. A bit dodgy.

An alternative would be to have both.

• Socio-Economic Factors - ONX-00001
  • current marital status - ONX-00001 (Enumerated List)
    • [RiskFactorQuestionnaire: What is your current marital status]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Living status(Enumerated List)
    • [RiskFactorQuestionnaire: Do you live with a spouse or partner]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • People living in household - ONX-00001 (Numeric)
    • [RiskFactorQuestionnaire: How many people live in your household]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Employment status - ONX-00001 (Enumerated List)
    • [RiskFactorQuestionnaire: What is your current work status]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Employment type - ONX-00001 (Enumerated List)
    • [RiskFactorQuestionnaire: Which of the following best describes the work you do or did]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]
  • Educational Status - ONX-00001 (Enumerated List)
    • [RiskFactorQuestionnaire: What was the highest level of education you completed]
    • Start Date: [RiskFactorQuestionnaire: QuestionnaireRun.timeStart]

Ignored Data

• EndContactQuestionnaire
  • Primary email address
  • Additional email address
• Most Consent fields
• Recruitment context?
• Sample Preliminary Questions?